Out-of-pocket spending and lack of adequate health policy support for people living with sickle cell disease in Nigeria may predispose to high economic burden and catastrophic cost.The objective of the study was to evaluate the economic burden and catastrophic cost of sickle cell disease patients in a Nigerian tertiary health institution.In this st
Blocked expression of key genes of the angiogenic pathway in JSRV-induced pulmonary adenocarcinomas
Abstract JSRV (Jaagsiekte Sheep Retrovirus) is a retrovirus inducing a transmissible lung adenocarcinoma in sheep and goats with predominantly Rattle Blanket lepidic and papillary lesions.This naturally occurring lung cancer in large animals shares many features with human pneumonic-type lung adenocarcinomas with predominant lepidic growth.The meta
Estimation of Head Accelerations in Crashes Using Neural Networks and Sensors Embedded in the Protective Helmet
Traumatic Brain Injuries (TBIs) are one of the most frequent and severe outcomes of a Powered Two-Wheeler (PTW) crash.Early diagnosis and treatment can greatly reduce permanent consequences.Despite the fact that devices to track Alignment Cam Plate Kit head kinematics have been developed for sports applications, they all have limitations, which ham
Enzyme-Loaded pH-Sensitive Photothermal Hydrogels for Mild-temperature-mediated Combinational Cancer Therapy
Photothermal therapy (PTT) that utilizes hyperthermia to ablate cancer cells is a promising approach for cancer therapy, while the generated high temperature may lead to damage of surrounding normal tissues and inflammation.We herein report the construction of glucose oxidase (GOx)-loaded hydrogels with a pH-sensitive photothermal conversion proper